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FOY 251

CAS No. 71079-09-9

FOY 251( —— )

Catalog No. M22400 CAS No. 71079-09-9

FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.FOY-251, an active metabolite of camostat mesilate, on sodium transport in the mouse cortical collecting duct cell line (M-1 cells) and on blood pressure in Dahl salt-sensitive rats.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    FOY 251
  • Note
    Research use only, not for human use.
  • Brief Description
    FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.FOY-251, an active metabolite of camostat mesilate, on sodium transport in the mouse cortical collecting duct cell line (M-1 cells) and on blood pressure in Dahl salt-sensitive rats.
  • Description
    FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.FOY-251, an active metabolite of camostat mesilate, on sodium transport in the mouse cortical collecting duct cell line (M-1 cells) and on blood pressure in Dahl salt-sensitive rats. Treatment with camostat mesilate or FOY-251 decreased equivalent current (Ieq) in M-1 cells in a dose-dependent manner and inhibited the protease activity of prostasin in vitro.
  • In Vitro
    FOY-251 represents a dose-dependent inhibition of equivalent current in M-1 cells.FOY-251 inhibits the proteolytic activity of prostasin.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    proteinase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    71079-09-9
  • Formula Weight
    409.41
  • Molecular Formula
    C17H19N3O7S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 20 mg/mL (48.85 mMul)
  • SMILES
    CS(O)(=O)=O.NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(CC(O)=O)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Maekawa A , Kakizoe Y , Miyoshi T , et al. Camostat mesilate inhibits prostasin activity and reduces blood pressure and renal injury in salt-sensitive hypertension[J]. Journal of Hypertension, 2009, 27(1):181.
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